For the last number of long rides, the cycling shorts I have grabbed out of the drawer have been my She-wool (or Smart-beest) hybrid shorts. Mind you, I have a BREATHTAKING number of cycling shorts; they all fit, but these are the ones I wear.
I reviewed the Smartwool Ewetopia shorts for Road Bike Review a couple of years ago. I really, really liked the fabric and the fit, except that I just couldn't wear the wool-faced chamois for any length of time.
Now, I have no reservations remodeling clothing that needs it. And I had an unattached Shebeest chamois (my all-time favorite one, I might add). After some quality time with a seam ripper, and some careful pinning and sewing (note: wooly nylon thread does not work in a standard sewing machine), I had the perfect pair.